Review Articles





1989
Tetrahymena telomerase contains an internal RNA template.
1990
How does the end begin? Formation and maintenance of telomeres in ciliates and yeast.
Telomeres, telomerase and senescence.
1991
Telomere loss: mitotic clock or genetic time bomb?
Structure and function of telomeres.
Telomeres.
1995
Unusual reverse transcriptases.
1996
Structure and function of telomerase.
The roles of telomeres and telomerase in cell life span.
1997
The telomere and telomerase: how do they interact?
Telomerase and the chromosome end replication problem.
Telomere control of replicative lifespan.
Lessons from mice without telomerase.
Telomerase is a true reverse transcriptase.
Telomerase is an unusual RNA-containing enzyme. A review.
Plant telomeres and telomerases. A review.
Chromosome ends: all the same under their caps.
1998
Telomeres and senescence: the history, the experiment, the future.
The telomerase reverse transcriptase: components and regulation.
Telomerase and chromosome end maintenance.
Telomerase enzyme activation and human cell immortalization.
1999
Telomerases.
Telomeres and telomerase: broad effects on cell growth.
Telomerase and the maintenance of chromosome ends.
Telomeres and telomerase: at the end, it all comes together.
Assembly and regulation of telomerase.
Ciliate telomerase biochemistry.
2000
Mammalian telomeres and telomerase.
Telomerase: not just black and white, but shades of gray.
The end of the (DNA) line.
Telomeres and their control.
2001
Telomeres.
2002
Telomerase regulation: not just flipping the switch.
Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again.
Telomeres, telomerase, and stability of the plant genome.
2003
Stem cells, telomerase and dyskeratosis congenita.
Dyskeratosis congenita.
Mouse models for telomere and telomerase biology.
Dyskeratosis congenita: its link to telomerase and aplastic anaemia.
Getting to the end: telomerase access in yeast and humans.
2004
Telomeres and telomerase.
Telomerase RNA structure and function: implications for dyskeratosis congenita.
Telomerase RNA: a flexible RNA scaffold for telomerase biosynthesis.
Telomeres and telomerase: a modern fountain of youth?
Adding to the ends: what makes telomerase processive and how important is it?
2005
Extratelomeric functions of telomerase.
The pleiotropy of telomerase against cell death.
2006
Structure and function of telomerase RNA.
The structure and function of telomerase reverse transcriptase.
Dyskeratosis congenita.
The biogenesis and regulation of telomerase holoenzymes.
Lasker Laurels for telomerase.
The unmasking of telomerase.
2007
Telomerase unplugged.
Mutations of telomerase complex genes linked to bone marrow failures.